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SELECT 
  cscart_ult_product_prices.product_id, 
  MIN(
    IF(
      cscart_ult_product_prices.percentage_discount = 0, 
      cscart_ult_product_prices.price, 
      cscart_ult_product_prices.price - (
        cscart_ult_product_prices.price * cscart_ult_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_ult_product_prices 
WHERE 
  cscart_ult_product_prices.product_id IN (
    5280, 5281, 5282, 5283, 5284, 5285, 5286, 
    5287, 5288, 5289, 5290, 5291, 5292, 
    5293, 5294, 5295, 5296, 5297, 5298, 
    1546, 1547, 1548, 1549, 1550, 1551, 
    1552, 1553, 1554, 1555, 1556, 1557, 
    1558, 1559, 1560, 1561, 1562, 1563, 
    1564, 1565, 1566, 1567, 1568, 1569, 
    1570, 1571, 5245, 5246, 5247
  ) 
  AND cscart_ult_product_prices.lower_limit = 1 
  AND cscart_ult_product_prices.company_id = 1 
  AND cscart_ult_product_prices.usergroup_id IN (0, 0, 1) 
GROUP BY 
  cscart_ult_product_prices.product_id

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}