SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    5449, 5450, 5451, 5452, 5453, 5454, 5455, 
    5456, 5457, 5458, 5459, 5460, 6727, 
    1672, 1673, 1674, 1675, 1676, 1677, 
    1678, 1679, 1680, 1681, 1682, 1683, 
    1684, 1685, 1686, 1687, 1688, 1689, 
    1690, 1691, 1692, 1693, 1694, 1695, 
    1696, 1697, 1698, 1699, 1700, 1701, 
    1702, 1703, 1704, 1705, 1706, 1707, 
    1708, 1709, 1710, 1711, 1712, 1713, 
    1714, 1715, 1716, 1717, 1718, 1719, 
    1720, 3733, 3735, 3736, 3737, 3738, 
    5371, 5372, 5373, 5374, 5375, 5376, 
    5377, 5378, 5379, 5380, 5381, 5382, 
    5383, 5384, 5385, 5386, 5387, 5388, 
    5389, 5390, 5391, 5392, 5393, 5394, 
    5395, 5396, 5397, 5398, 5399
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00148

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "67.21"
    },
    "grouping_operation": {
      "using_filesort": false,
      "table": {
        "table_name": "cscart_product_prices",
        "access_type": "range",
        "possible_keys": [
          "usergroup",
          "product_id",
          "lower_limit",
          "usergroup_id"
        ],
        "key": "product_id",
        "used_key_parts": [
          "product_id"
        ],
        "key_length": "3",
        "rows_examined_per_scan": 96,
        "rows_produced_per_join": 19,
        "filtered": "20.00",
        "index_condition": "(`gaseus`.`cscart_product_prices`.`product_id` in (5449,5450,5451,5452,5453,5454,5455,5456,5457,5458,5459,5460,6727,1672,1673,1674,1675,1676,1677,1678,1679,1680,1681,1682,1683,1684,1685,1686,1687,1688,1689,1690,1691,1692,1693,1694,1695,1696,1697,1698,1699,1700,1701,1702,1703,1704,1705,1706,1707,1708,1709,1710,1711,1712,1713,1714,1715,1716,1717,1718,1719,1720,3733,3735,3736,3737,3738,5371,5372,5373,5374,5375,5376,5377,5378,5379,5380,5381,5382,5383,5384,5385,5386,5387,5388,5389,5390,5391,5392,5393,5394,5395,5396,5397,5398,5399))",
        "cost_info": {
          "read_cost": "65.29",
          "eval_cost": "1.92",
          "prefix_cost": "67.21",
          "data_read_per_join": "460"
        },
        "used_columns": [
          "product_id",
          "price",
          "percentage_discount",
          "lower_limit",
          "usergroup_id"
        ],
        "attached_condition": "((`gaseus`.`cscart_product_prices`.`lower_limit` = 1) and (`gaseus`.`cscart_product_prices`.`usergroup_id` in (0,1)))"
      }
    }
  }
}