SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (
    12160, 12161, 12162, 12163, 12164, 12165, 
    12166, 12167, 12168, 12169, 12170, 
    12171, 12172, 12173
  ) 
  AND feature_id IN (553, 622) 
  AND lang_code = 'en'

Query time 0.00278

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "12.23"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "PRIMARY",
      "used_key_parts": [
        "feature_id",
        "product_id"
      ],
      "key_length": "6",
      "rows_examined_per_scan": 52,
      "rows_produced_per_join": 22,
      "filtered": "42.69",
      "using_index": true,
      "cost_info": {
        "read_cost": "10.01",
        "eval_cost": "2.22",
        "prefix_cost": "12.23",
        "data_read_per_join": "17K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`gaseus`.`cscart_product_features_values`.`product_id` in (12160,12161,12162,12163,12164,12165,12166,12167,12168,12169,12170,12171,12172,12173)) and (`gaseus`.`cscart_product_features_values`.`feature_id` in (553,622)) and (`gaseus`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}

Result

product_id feature_id variant_id
12160 553 1324
12161 553 1324
12162 553 1324
12163 553 1324
12164 553 1324
12165 553 1324
12166 553 1324
12167 553 2197
12168 553 2197
12169 553 2197
12170 553 2197
12171 553 2197
12172 553 2197
12173 553 2197
12160 622 2189
12161 622 2158
12162 622 2159
12163 622 2160
12164 622 2155
12165 622 2156
12166 622 2157
12167 622 2189
12168 622 2158
12169 622 2159
12170 622 2160
12171 622 2155
12172 622 2156
12173 622 2157